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Ron
Board Staff
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Posted: Mon Sep 1st, 2008 20:49 |
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Symptoms: carpal tunnel, sore hands sometimes
Date: 20 August 2008
Sample was probably frozen
Not avoiding foods with D, not avoiding sun.
Not supplementing D, no meds or other supplements.
1,25-D: 86.9 pmol/L = 36.2 pg/ml
25-D: 118 nmol/L = 47.2 ng/ml
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P.Bear R.N.
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Posted: Tue Sep 2nd, 2008 18:55 |
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Ron,
Your 1,25-D is elevated at 36.2pg/ml (the population average is 25-29 pg/ml). It is 0.76 sigma high and based on population studies, 77.65 % of the population would be expected to have a lower number. Your inflammation may be in tissues (nerves, joints, tendons)not well perfused by blood, in which case the effected tissue levels would be much higher.
Your 25-D of 47.2ng/ml is very high and reflects your reported non avoidance of D and sunlight. Because 25-D is immunosuppressive, you need to avoid ALL sources of Vitamin D to get it down to a therapeutic level of 12ng/ml or less. Please see Foods To Avoid and The importance of avoiding vitamin D.
"The 25-D seems to be the most critical factor as to whether the immune system is able to start working. Any level of 25-D above about 20ng/ml is likely to be acting as an immunosuppressant, with an action very similar to that of corticosteroids." Dr. Trevor Marshall, Ph.D.
Your D-tests, diagnosis and symptoms may indicate Th1 inflammation. Please see Symptoms of Hypervitaminosis-D and you may recognize a few more. You will not get well and your health will continue to deteriorate if you don't treat the underlying bacterial cause of Th1 inflammation with the MP. Please see Is the MP an applicable treatment for my disease?
Most supplements and many medications must be avoided on the MP.
Our clinical study is temporarily closed to enrollment. As vacancies occur, we will admit subjects based on an application. To obtain an application forum, please send an email to marshallprotocol2@yahoo.com with 'request MP application' in the subject line.
Best,
____________________
Nothing in this site should be considered medical advice. Sorry, My private message function has been disabled and I can not read any posts. I have never been "inactive" but have been using PMs to help patients to help their physicians with care
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Ron
Board Staff
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Posted: Wed Sep 3rd, 2008 19:31 |
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Thank you P.Bear.
Today I received the lab results on paper (by the drawing lab) and our family doctor apparently made a reading error while on the phone with me:
Date: 13 August 2008
1,25-D: 118 pmol/L = 49.1 pg/ml
25-D: 104 nmol/L = 41.6 ng/ml
So the value 118 belonged to the 1,25-D test. 
I know that this sample was not frozen because they refused to do so. That's why I returned the week following after I made sure the drawing lab got better instructions from the diagnosing lab.
Date: 20 August 2008
1,25-D: 86.9 pmol/L = 36.2 pg/ml
But now all involved parties (drawing lab, diagnosing lab and family doc) have definitely proven to be unreliable I'm not sure what to think. The (still very high) 25-D level does not reflect my diet nor do I ever sunbath, on the contrary. I ditched margarine over a year ago which I think is about the only food that is fortified in this country. I rarely eat processed food anyway. I do have mushrooms, fish and eggs but all in modesty. 
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P.Bear R.N.
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Posted: Thu Sep 4th, 2008 18:31 |
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Ron,
Your 1,25-D is elevated at 49.2pg/ml (the population average is 25-29 pg/ml). It is 2.13 sigma high and based on population studies, 98.4% of the population would be expected to have a lower number. If sample was not frozen the number would have been even higher for both you and your wife.
Your 1,25-D is above the maximum of 45pg/ml listed in the Merck Manual of Diagnosis and Therapy (15 Oct 2006 online). At levels above about 42 pg/ml, the 1,25-D (generated by the Th1 inflammation) begins to stimulate bone osteoclasts, causing bone to be resorbed (dissolved) back into the bloodstream. Not only does this lead to osteoporosis, but also to calcium being deposited into soft tissue of the body, including the lungs, breasts, and the kidneys (where it forms kidney stones). Please see Osteoporosis, osteopenia and Th1 illness.
I might look for a hidden source of D in your foods. Fish can have quite a bit, as can medicinal mushrooms and many pork products and egg yolks.
best, P.B.
____________________
Nothing in this site should be considered medical advice. Sorry, My private message function has been disabled and I can not read any posts. I have never been "inactive" but have been using PMs to help patients to help their physicians with care
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Ron
Board Staff
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Posted: Thu Sep 4th, 2008 22:22 |
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Thanks P.Bear.
Tonight I had risotto al fungi for dinner but without the fungi. 
When I find out more I'll post it here.
Ron
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Ron
Board Staff
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Posted: Wed Oct 8th, 2008 21:01 |
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Here are the results of another D-metabolites test:
Date: 24 September 2008
1,25-D: 118pmol/L = 49.1 pg/ml
25-D: 51.7 nmol/L = 20.7 ng/ml
The 25-D test was done by the hospital lab that also drew the blood. I think that the extremely high value of 104 nmol/L, that was supposedly measured six weeks earlier, must have been a mistake. A lot of MP-ers would wish for their 25-D-level to drop like that..
My Dad saw his 25-D levels drop from 104 to 29 nmols/L in an even shorter period of time. Indeed, we both had exactly the same high level, reported by the same lab, around the same date. What are the odds...
Likewise, I find it very suspicious to see the exact same level of 118 pmol/L reported for 1,25-D.
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P.Bear R.N.
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Posted: Thu Oct 9th, 2008 06:04 |
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Ron, As you know these results also indicate TH1 inflammation but the lower 25-D level would mean your innate immune response would not be as diminished as it was with higher level. It is always frustrating when labs seem to make errors and some seem to do so often with these tests; but at least it is not an urgent situation where a lab error might cause a potential for immediate harm as in ICU or ER medicine.
best, P.B.
____________________
Nothing in this site should be considered medical advice. Sorry, My private message function has been disabled and I can not read any posts. I have never been "inactive" but have been using PMs to help patients to help their physicians with care
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