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D-results for my son
 Moderated by: P.Bear R.N., Admin  

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GreenEcoBean
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Joined: Wed Jul 30th, 2008
Location: Macon, Georgia USA
Posts: 5
Status:  Offline
 Posted: Fri Aug 1st, 2008 15:25

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This test was originally done to start a Vitamin K protocol for my son who has autism, severe dyslexia, OCD, allergies.

Date blood was drawn:    10/12/2007

Lab doing testing:  Spectrum Laboratory Network

Was sample frozen: Not sure, probably not.

Avoiding foods with D: Not yet

Avoiding sun: No

Meds/Supps:  CoQ10, Olive Leaf Extract, L-Carnitine, Fish Oil (not Cod), Vitamin K2, Multi, B-Complex, Probiotics.

Pred or similar: No

Vitamin D/Fish Oil: Fish oil for 5 years

Taking Benicar: No

ARB or ACE inhibitor:  No

Results:      

1,25 - Dihydroxy                               50 pg/mL

25- Hydroxy                                      21 ng/mL

Calcium, Ionized                               1.32 mmol/L

Vitamin A, Serum or Plasma
Retinol (Vitamin A)                               0.32 mg/L
Retinyl Palmitate                                  0.01 mg/L
Vitamin A Interpretation                    Normal
Sample exposed to light

Calcium                                             9.2 mg/dL

Osteocalcin by ECIA                            83 ng/mL



Thank you!



____________________
Jane
Dx - RA (not official, but ANA very high)
Only restricted diet so far (SCD) and working on the Vit. D portion.
Mama to
Erik 11 (autism, severe dyslexia)
Julie 8 (asthma)
Christopher 16 mo (NT so far...and still BF)
P.Bear R.N.
Research Staff


Joined: Sun Oct 14th, 2007
Location: Ozark Border, Missouri USA
Posts: 232
Status:  Online
 Posted: Sat Aug 2nd, 2008 05:34

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GreenEcoBean,

1,25-D is elevated at  50 pg/ml (the population average is 25-29 pg/ml). It is 2.21 sigma high and based on population studies,  98.65% of the population would be expected to have a lower number.

 1,25-D is above the maximum of 45pg/ml listed in the Merck Manual of Diagnosis and Therapy (15 Oct 2006 online). At levels above about 42 pg/ml, the 1,25-D (generated by the Th1 inflammation) begins to stimulate bone osteoclasts,  causing bone to be resorbed (dissolved) back into the bloodstream. Not only does this lead to osteoporosis, but also to calcium being deposited into soft tissue of the body, including the lungs, breasts, and the kidneys (where it forms kidney stones). Please see Osteoporosis, osteopenia and Th1 illness.

25-D of   21 ng/ml is high enough to blunt innate immune response and reflects your son's reported vitamin D supplementation in olive leaf extract, fish oill and multivitamin. Because 25-D is immunosuppressive, he needs to avoid ALL sources of Vitamin D to get it down to a therapeutic level of 12ng/ml or less. Please see Foods To Avoid and The importance of avoiding vitamin D.

 "The 25-D seems to be the most critical factor as to whether the immune system is able to start working. Any level of 25-D above about 20ng/ml is likely to be acting as an immunosuppressant, with an action very similar to that of corticosteroids." Dr. Trevor Marshall, Ph.D.


Your son's D-tests, diagnosis and symptoms indicate Th1 inflammation. Please see Symptoms of Hypervitaminosis-D and you may recognize a few more. He will not get well and his health will continue to deteriorate if you don't treat the underlying bacterial cause of Th1 inflammation with the MP. Please see Is the MP an applicable treatment for my disease?

Most supplements and many medications must be avoided on the MP.

Our clinical study is temporarily closed to enrollment. As vacancies occur, we will admit subjects based on an application. To obtain an application forum, please send an email to marshallprotocol2@yahoo.com  with 'request MP application' in the subject line.
best, P.B.



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