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D-Metabolites/Labs
 Moderated by: P.Bear R.N., Admin  

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caroldeleah
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Joined: Mon Jan 21st, 2008
Location: USA
Posts: 50
Status:  Offline
 Posted: Tue Jul 29th, 2008 01:53

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Diagnosis/Symptoms:  Chronic Idiopathic Uveitis:  Refractive Myopia, Blurry Vision, Early Cataract, IOP, Joint Pain, Recurring lump in ear lobe;  Hashimotos Thyroiditis:  Thyroid Nodule

                          7/21/08        2/25/08*        1/22/08*

1,25D (PG/ML)       37                 16                 --

25-D   (NG/ML)       28                 23                19

*See previous posting 3/7/08

Lab:  Quest

Frozen:  Uncertain/MP instructions given to lab

Avoiding Foods with D:  No

Avoiding sun/lights:  No

Rx & OTC:  Uveitis:  Pred Forte 1%--1 drop rt eye Bid,                                                                   IOP: Timolol 0.5%--1 drop rt eye Bid   Hypothyroidism: Levoxyl 75mcg--OD

Prednisone/Immunosuppressants:  Prednisone:  Aug 07 dc,   Pred Forte:  4/07 to 1/31/08, 4/8/08 to 6/3/08, 6/25/08 to present,    Methotrexate:  intermittently--12/13/07 to 5/26/08 dc,   Beclomethasone:  One puff Bid 10/7/05 to 2/08 dc

Vitamin D Supplements:  No

Benicar:  No

ARB or ACE inhibitor:  No

Labs:     % Lymphocytes:   7/21/08--38%   6/11/08--32%   (13-41%)

              CRP:                     7/21/08--1.6      11/29/07--1.4   (0-9.0mg/L)

              Alk Phosphat        7/21/08--68        6/11/08--63     (100-320U/L)

              Creatinine            7/21/08--0.7       6/9/08--0.6      (0.5-1.0mg/dl)

              BUN                      7/21/08--12        6/11/08--12     (5-20mg/dl)

              Hemoglobin          7/21/08--13.8     6/11/08--12.6  (12.0-16.0g/dl)

              Hematocrit            7/21/08--40.3     6/11/08--36.4  (37.0-45.0%)

              Free T4                 7/21/08-- 0.86                             (0.55-1.61ng/dL)            

              Free T4                 5/14/08--1.32                              (0.9-1.70ng/dL)

              TSH                       7/21/08--1.61                              (0.60-6.18uIU/ml)

              TSH                       5/14/08--1.72                              (0.27-4.20uIU/ml)

These are the lab results for my daughter, age 17

 

 

 



____________________
Uveitis/Hashimotos/Hypothyroidism/Thyroid Nodule/Arthralgias/RefractiveMyopia/1,25D34/ Ph1Aug08/Ph2Nov08/25D14(10/08)/Combigan/Cytomel/RefreshPlusSgl
NoIRs/LowLuxHome/CoverUp/Sunscreen
P.Bear R.N.
Research Staff


Joined: Sun Oct 14th, 2007
Location: Ozark Border, Missouri USA
Posts: 233
Status:  Online
 Posted: Tue Jul 29th, 2008 09:06

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 Daughter and Caroldeleah,

Your 1,25-D is elevated at  37 pg/ml (the population average is 25-29 pg/ml). It is 0.84 sigma high and based on population studies,  79.95 % of the population would be expected to have a lower number.

Your 25-D of  28 ng/ml is high enough to mute innate immune response.  Because 25-D is immunosuppressive, you need to avoid ALL sources of Vitamin D to get it down to a therapeutic level of 12ng/ml or less. Please see Foods To Avoid and The importance of avoiding vitamin D.

Your other labs all look fine but I would recommend a Free T3 level be drawn. T4 and TSH levels can be fine but T3 levels can still be low.

THYROID DISEASE and Th1 inflammation

 "The 25-D seems to be the most critical factor as to whether the immune system is able to start working. Any level of 25-D above about 20ng/ml is likely to be acting as an immunosuppressant, with an action very similar to that of corticosteroids." Dr. Trevor Marshall, Ph.D.

Your D-tests, diagnosis and symptoms indicate Th1 inflammation. Please see Symptoms of Hypervitaminosis-D and you may recognize a few more. You will not get well and your health will continue to deteriorate if you don't treat the underlying bacterial cause of Th1 inflammation with the MP. Please see Is the MP an applicable treatment for my disease?

Most supplements and many medications must be avoided on the MP.

Our clinical study is temporarily closed to enrollment. As vacancies occur, we will admit subjects based on an application. To obtain an application forum, please send an email to marshallprotocol2@yahoo.com  with 'request MP application' in the subject line.

Best, P.B.



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