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jessica
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| Joined: | Mon Jul 28th, 2008 |
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| Posts: | 1 |
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Posted: Mon Jul 28th, 2008 21:26 |
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Hi,
I had my D metabolites tested as an exploratory measure before possibly starting the MP. I would be grateful if you could help me interpret the results. Thanks.
- Symptoms: Anxiety, depression, hypomanic disorder, PMDD, fatigue
- Date collected: May 08, 2008
- Lab: Lifelabs, Victoria, Canada
- Sample was frozen for shipment
- Have not been avoiding foods with vitamin D in them
- At the time the blood was taken (May), I had been minimally exposed to the sun for ~ 8 months (northern fall/winter). I hadn't been avoiding indoor lights.
- Paroxetine/Paxil for anxiety and depression; selenium, zinc, vitamin C for immune support; B complex for anxiety; Valerian root and Oat extract for anxiety.
- No prednisone etc.
- No Vitamin D supplements; took fish oils occasionally in the fall (Oct/Nov 08) with food
- No Benicar
- No ARB or ACE inhibitors
1,25D: 87.5 pg/ml
25D: 25.6 ng/ml
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Depression, anxiety, fatigue 1,25D87.5
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P.Bear R.N.
Research Staff
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Posted: Tue Jul 29th, 2008 08:36 |
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Jessica,
Your 1,25-D is very elevated at 87.5pg/ml (the population average is 25-29 pg/ml). It is 5.89 sigma high and based on population studies, 100 % of the population would be expected to have a lower number.
Your 1,25-D is above the maximum of 45pg/ml listed in the Merck Manual of Diagnosis and Therapy (15 Oct 2006 online). At levels above about 42 pg/ml, the 1,25-D (generated by the Th1 inflammation) begins to stimulate bone osteoclasts, causing bone to be resorbed (dissolved) back into the bloodstream. Not only does this lead to osteoporosis, but also to calcium being deposited into soft tissue of the body, including the lungs, breasts, and the kidneys (where it forms kidney stones). Please see Osteoporosis, osteopenia and Th1 illness.
Your level of elevation suggests inflammation in major organs such as heart, liver and lungs.
When should I be concerned about cardiac symptoms?
Your 25-D of 25.6ng/ml is high enough to dampen innate immune response. Because 25-D is immunosuppressive, you need to avoid ALL sources of Vitamin D to get it down to a therapeutic level of 12ng/ml or less. Please see Foods To Avoid and The importance of avoiding vitamin D.
"The 25-D seems to be the most critical factor as to whether the immune system is able to start working. Any level of 25-D above about 20ng/ml is likely to be acting as an immunosuppressant, with an action very similar to that of corticosteroids." Dr. Trevor Marshall, Ph.D.
Your D-tests, diagnosis and symptoms indicate Th1 inflammation. Please see Symptoms of Hypervitaminosis-D and you may recognize a few more. You will not get well and your health will continue to deteriorate if you don't treat the underlying bacterial cause of Th1 inflammation with the MP. Please see Is the MP an applicable treatment for my disease?
Most supplements and many medications must be avoided on the MP.
Our clinical study is temporarily closed to enrollment. As vacancies occur, we will admit subjects based on an application. To obtain an application forum, please send an email to marshallprotocol2@yahoo.com with 'request MP application' in the subject line.
best, P.B.
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Nothing contained in this site is or should be considered, or used as a substitute for, medical advice, diagnosis or treatment by your physician.
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