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Alejandro
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| Joined: | Mon Nov 17th, 2008 |
| Location: | Germany |
| Posts: | 25 |
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Posted: Mon Nov 17th, 2008 16:22 |
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Hi, probably one of the first test results from Germany.
Background information:
Date: November 14th 2008
Lab: German lab near Heidelberg, no details about how the test was done.
Sunlight: no special care
Vitamin D: no vitamin D food since 4 days before analysis
Supplements: Multivitamins for years, since 2 weeks stopped
Benicar: (Olmetec in Germany) 10 mg /day since January 2008. Daily
Pravastatin 40mg daily
1,25 D3: 63 ng/l (same as pg/ml)
25 D : 22 micro g/l (same as ng/ml)
Calcium: 2,62 mmol/l (maxium according lab range is 2,65)
Next blood test will be in few months.
Skin Sarcoidosis, treated with corticoid creme 4 years ago
Current symptoms; fatigue, several problems with back, blockades
Thanks a lot
AlexLast edited on Mon Nov 17th, 2008 16:40 by Alejandro
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Skin Sarcoidosis treated with Corticoid creme, no MP yet. Thinking about starting MP soon. Low Vitamin D diet.
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Dr Trevor Marshall
Research Team
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Posted: Mon Nov 17th, 2008 16:41 |
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There are many MP members from Germany. A private conference was held in Berlin in September 2006 and I am told nearly a hundred attended, many of them on the protocol. Hopefully you will be able to connect with that group.
Your D metabolite tests show 1,25-D at a high level, so I suspect your sample was handled properly.
45pg/ml is the 2-sigma high point, and you are well above that, indicative of a highly dysregulated D metabolism.
Your 25-D is a little high, indicating supplementation in the past, indicative of the supplementation. I am guessing you are already working on getting that down into the single digit therapeutic range 
Your calcium will hopefully drop into a median range as the supplements stop, but you might want to keep an eye on that.
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Alejandro
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| Joined: | Mon Nov 17th, 2008 |
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Posted: Mon Nov 17th, 2008 16:46 |
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thanks a lot!
I forgot to mentioned that I let measure ACE as well, it was 50 U/L (maximum is 60).
As a first start, I plan to elevate the Benicar (olmetec) dosis to 20-40 mg daily. At the very beginning I started with 20 mg but I could not tolerate it. May be the 2nd attempt will succeed.
I would love to join the German group. If you have some references on the web, they will be appreciated.
Alex
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Skin Sarcoidosis treated with Corticoid creme, no MP yet. Thinking about starting MP soon. Low Vitamin D diet.
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Dr Trevor Marshall
Research Team
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Posted: Mon Nov 17th, 2008 17:00 |
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It is important that your Doctor understands that it is necessary to follow exactly the MP guideline documents. It is absolutely wrong to try and ramp the dose of Benicar, you are not the first to fail.
Please make sure that Doc is familiar with the FAQ and Essential infor topics at the main study site. Else you will likely end up very ill indeed.
http://www.marshallprotocol.com/forum2/
http://www.marshallprotocol.com/forum32/
http://www.marshallprotocol.com/forum37/
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Alejandro
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Posted: Mon Nov 17th, 2008 17:30 |
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Thanks again for this important advice.
In deed I am not taking Benicar for the MP but as a medicine against high blood pressure. As I started, I was not aware of MP. At that time 20 mg was prescripted.
I understand from the Guidelines that Statins should be discontinued as there is a risk of muscle damage (and hearth is a muscle..)
What to do with high colesterol levels during MP ? Should be just tolerated?
Thanks a lot
Alex
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Skin Sarcoidosis treated with Corticoid creme, no MP yet. Thinking about starting MP soon. Low Vitamin D diet.
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Dr Trevor Marshall
Research Team
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Posted: Mon Nov 17th, 2008 17:35 |
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Don't we have an FAQ explaining about management of Cholesterol levels?
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Alejandro
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Posted: Mon Nov 17th, 2008 17:39 |
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I found it!
http://www.marshallprotocol.com/view_topic.php?id=1198&forum_id=32
Thanks!
Alex
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Skin Sarcoidosis treated with Corticoid creme, no MP yet. Thinking about starting MP soon. Low Vitamin D diet.
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P.Bear R.N.
Research Staff
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Posted: Mon Nov 17th, 2008 20:53 |
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Alejandro,
Your 1,25-D is elevated at 63pg/ml (the population average is 25-29 pg/ml). It is 3.58 sigma high and based on population studies, 100% of the population would be expected to have a lower number.
Your 1,25-D is above the maximum of 45pg/ml listed in the Merck Manual of Diagnosis and Therapy (15 Oct 2006 online). At levels above about 42 pg/ml, the 1,25-D (generated by the Th1 inflammation) begins to stimulate bone osteoclasts, causing bone to be resorbed (dissolved) back into the bloodstream. Not only does this lead to osteoporosis, but also to calcium being deposited into soft tissue of the body, including the lungs, breasts, and the kidneys (where it forms kidney stones). Please see Osteoporosis, osteopenia and Th1 illness.
Your level of elevation suggests inflammation in major organs such as the heart, liver and lungs.
When should I be concerned about cardiac symptoms?
Your 25-D of 22ng/ml is high enough to somewhat dampen innate immune response. Because 25-D is immunosuppressive, you need to avoid ALL sources of Vitamin D to get it down to a therapeutic level of 12ng/ml or less. Please see Foods To Avoid and The importance of avoiding vitamin D.
"The 25-D seems to be the most critical factor as to whether the immune system is able to start working. Any level of 25-D above about 20ng/ml is likely to be acting as an immunosuppressant, with an action very similar to that of corticosteroids." Dr. Trevor Marshall, Ph.D.
Your ACE being towards the upper normal limit would be further confirmation of inflammation.
Your D-tests, diagnosis and symptoms indicate Th1 inflammation. Please see Symptoms of Hypervitaminosis-D and you may recognize a few more. You will not get well and your health will continue to deteriorate if you don't treat the underlying bacterial cause of Th1 inflammation with the MP. Please see Is the MP an applicable treatment for my disease?
Most supplements and many medications must be avoided on the MP.
Our clinical study is closed to enrollment.
best, P.B.
Last edited on Mon Nov 17th, 2008 20:57 by P.Bear R.N.
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Nothing contained in this site is or should be considered, or used as a substitute for, medical advice, diagnosis or treatment by your physician.
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Alejandro
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Posted: Mon Nov 17th, 2008 21:40 |
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Thanks a lot for your additional comments!
Alex
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Skin Sarcoidosis treated with Corticoid creme, no MP yet. Thinking about starting MP soon. Low Vitamin D diet.
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Alejandro
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Posted: Mon Jan 5th, 2009 09:58 |
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I got today the latest results. After two months on low Vitamin D diet (plus 10mg Benicar due to high BP)
the D-Metabolites values are now:
1,25 D3 : 43 ng/l (was 63)
25 D : 17 mikrog/l (was 22)
So the 1,25D Value is now below the allowed value by Merck manual and 25D is moving in the right direction. I hope some bacteria are being killed now.
Despite of some light head eaches (light herx?) I feel better now, brain fog is gone.
kind regads,
AlexLast edited on Mon Jan 5th, 2009 09:59 by Alejandro
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Skin Sarcoidosis treated with Corticoid creme, no MP yet. Thinking about starting MP soon. Low Vitamin D diet.
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