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Lin01
Member
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Posted: Thu Oct 2nd, 2008 22:46 |
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Vitamin D, 1,25-DIHYDROXY 58 pg/mL
Vitamin D, 25-HYDROXY Total 14 ng/mL
Vitamin D, 25-OH, D3 14 ng/mL
Vitamin D, 25-OH, D2 <4 ng/mL
Date the blood was drawn: 9/4/08
Which lab did the tests? Quest Diagnostics
Was the 1,25-D sample frozen for shipment? I assume it was; I asked about it's proper shipment procedure at time of draw
How long have you been avoiding foods with vitamin D in them? Several months generally, but not 100%; occasionally I will have a little cheese or ice cream, but not very often
How long have you been avoiding sun/lights? Not avoiding
List all meds, supplements (both prescription and OTC) you have been taking and why: levothyroxine/hypothyroid; vitamin C/scratchy throat avoidance; Vitamin B12 (without added folic acid)/energy level; occasional Extra Strength Excedrin/headaches, body aches
When and for how long have you taken prednisone or any other immunosuppressant in any form? Prednisone years ago (1984-5) for several months (not longer than 6 months), and occasionally since then during flare-ups (7 day reducing dose) perhaps 5 times between 1999 and 2005; also twice cortisone injections in neck/shoulder in 2003 or 4. Once I identified seafood, particularly tuna as the culprit, symptoms subsided and further medication by prednisone or cortisone was not required.
When and for how long did you take Vitamin D supplements (including any vitamin-mineral supplements), omega-3 supplements and/or any kind of fish oil? In time period between 1999 and 2003, I occasionally took multi-vitamins, ate tuna 2 to 3 times per week, and for about 6 months took a supplement made from shark cartilage until I discovered it and seafood was responsible for polymyositis-like symptoms.
Were you taking Benicar when the sample was drawn? No
Were you taking an ARB or or an ACE inhibitor when the sample was drawn? No
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Pulmonary sarcoidosis; hypothyroid; Eagle's Syndrome; Dupuytren's contracture rt hand; 1,25D 58 pg/mL; not yet on MP; levothyroxine
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P.Bear R.N.
Research Staff
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Posted: Fri Oct 3rd, 2008 23:04 |
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Lin101,
Your 1,25-D is elevated at 58pg/ml (the population average is 25-29 pg/ml). It is 3.05 sigma high and based on population studies, 99.90% of the population would be expected to have a lower number.
Your 1,25-D is above the maximum of 45pg/ml listed in the Merck Manual of Diagnosis and Therapy (15 Oct 2006 online). At levels above about 42 pg/ml, the 1,25-D (generated by the Th1 inflammation) begins to stimulate bone osteoclasts, causing bone to be resorbed (dissolved) back into the bloodstream. Not only does this lead to osteoporosis, but also to calcium being deposited into soft tissue of the body, including the lungs, breasts, and the kidneys (where it forms kidney stones). Please see Osteoporosis, osteopenia and Th1 illness.
Your level of elevation suggests inflammation in major organs such as the heart, liver and lungs.
When should I be concerned about cardiac symptoms?
Your 25-D of 14ng/ml is good and reflects your reported vitamin D avoidance and high 1,25-D. Because 25-D is immunosuppressive, you still need to avoid ALL sources of Vitamin D to get it down and keep it down to a therapeutic level of 12ng/ml or less. Please see Foods To Avoid and The importance of avoiding vitamin D.
"The 25-D seems to be the most critical factor as to whether the immune system is able to start working. Any level of 25-D above about 20ng/ml is likely to be acting as an immunosuppressant, with an action very similar to that of corticosteroids." Dr. Trevor Marshall, Ph.D
Your D-tests, diagnosis and symptoms indicate Th1 inflammation. Please see Symptoms of Hypervitaminosis-D and you may recognize a few more. You will not get well and your health will continue to deteriorate if you don't treat the underlying bacterial cause of Th1 inflammation with the MP. Please see Is the MP an applicable treatment for my disease?
Most supplements and many medications must be avoided on the MP.
Our clinical study is currently closed to enrollment.
best,P.B.
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Nothing contained in this site is or should be considered, or used as a substitute for, medical advice, diagnosis or treatment by your physician.
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