 |
| Author | Post |
|---|
vip.5678
Member
| Joined: | Fri Sep 5th, 2008 |
| Location: | |
| Posts: | 12 |
| Status: |
Offline
|
|
Posted: Fri Sep 26th, 2008 19:10 |
|
Dear Moderator,
Today I got my test results for D-Metabolites. As I was required to post here for interpretation, I am doing so. I will appreciate a thorough investigation.
Problem Description: My main problem is severe fatigue both mental and physical. I don't sleep, many a times I just keep lying on bed all night, next morning I feel like sleeping but I don't sleep.
It all started 2.5 years back. Slowly and slowly it (fatigue) has become quite severe. Diminishing memory and cognitive skills are associated symptoms. Since, last few weeks I have also started experiencing chest pain.
Diagnosis: After exploring endocrinology and many other things like Lyme Disease, I don't have a diagnosis yet. At Quest Lab, USA, I tested negative for Lyme (Bacteria Borrelia). Even Lyme can give symptoms like these. I have many tests from endocrinology like ACTH, Cortisol, Sex Hormones etc.
I did a self diagnosis of CFS (Chronic Fatigue Syndrome). However, I don't feel pain anywhere in the body, it's loosness in the joints, loss of muscles, severe fatigue all over body. My fatigue doesn't worsens after little bit of exercises, as it happens in some cases of CFS, it's that I can't jog or exercise much. (Just 500-600 meters and that's it).
Past History : I have a long history of chronic depression. However, my depression was completely cured by a particular form of meditation known as vipassana meditation. During my depression I wasn't having symptoms of fatigue, and physical weakness. It was all in the mind.
There was a point of time when I went through severe emotional stress, I wasn't cured of depression, lost my scholarship and job at university. I also went through chronic sleep deprivation. Slowly and slowly fatigue started. I gave up everything.
After coming across this meditation and practicing it for almost 1.5 years, my depression and emotional crisis are completely gone. Today, I am left with severe fatigue.
My objective of giving past history is just to give moderators a medical background of self.
Marshall Protocol & D-Metabolities Results: I came across MP just 1 month back.
Tests were done at Quest Lab in USA (Nicholas Institute, CA), sample was shipped from my home country. Lab was instructed to follow sample collection procedure as is given on MP website.
Lab Date :09/09/2008. I am a 32 years old Male.
1. VITAMIN D, 25 - OH, TOTAL : 15 ng/mL [ Range 20 - 100] , Low
a. VITAMIN D, 25 - OH, D3 : 15 ng/mL
b. VITAMIN D, 25 - OH, D2 : < 4 ng/mL
2. VITAMIN D, 1, 25-DIHYDROXY : 32 pg/ml [ Range 15 - 60]
According to test reports, I am deficient in Vitamin D. They suggest an optimal level of > 30 ng/mL.
I am a vegetarian. In my knowledge I don't overconsume or supplement vitamin D. My exposure to sunlight is normal. I am not on any type of medication. For last 3 months or so I haven't taken any medication. 5 months back I tried 20 mg of hydrocortisone for 3 weeks or so. At the same time I consumed one capsule /day of fish oil sporadically.
I can say these D-metabolites tests were done on a clean slate.
In my personal opinion I think my HPA (Hypothalumus-Pituitary-Adrenal) axis is damaged, because of long chronic stress that I went through. I have done some reading on this and there are some case studies pointing towards long chronic stress / sleep deprivation and CFS.
I have my ACTH (pituitary hormone), cortisol, ACTH Stim test results (many more). If it can be helpful in interpretation along with D-metabolites. I am low on ACTH.
I am yet learning MP. Sorry, for being long. I would like thank you for your time and effort.
Sincerely,
Joy.
|
P.Bear R.N.
Research Staff
|
Posted: Fri Sep 26th, 2008 20:45 |
|
vip.5678,
Your 1,25-D is only slightly above average at 32pg/ml. It is 0.32 sigma high and based on population studies, 62.55 % of the population would be expected to have a lower number. The population average is 25-29 pg/ml and it is above-average 1,25-D levels (hypervitaminosis-D) that cause many troublesome symptoms. Since you report many troublesome symptoms, either the lab result is in error or your paracrine (tissue) level of 1,25-D is much higher than the measured serum level. This sometimes occurs when the inflammation is in tissues not well perfused by blood (for example nerves, joints).
Your 25-D level of 15ng/ml is fairly typical in vegetarians who are not taking D. Because 25-D is immunosuppressive, you would still need to avoid ALL sources of Vitamin D to get it down and keep it down to a therapeutic level of 12ng/ml or less. Please see Foods To Avoid and The importance of avoiding vitamin D.
"The 25-D seems to be the most critical factor as to whether the immune system is able to start working. Any level of 25-D above about 20ng/ml is likely to be acting as an immunosuppressant, with an action very similar to that of corticosteroids." Dr. Trevor Marshall, Ph.D.
As your tests are ambiguous, you have the option to retest (which isn't necessary unless Doc insists) or to do a therapeutic probe which is our recommendation. Your diagnosis and symptoms would seem to indicate Th1 inflammation. Please see Symptoms of Hypervitaminosis-D and you may recognize a few more. If infected you will not get well and your health will continue to deteriorate if you don't treat the underlying bacterial cause of Th1 inflammation with the MP. Please see Is the MP an applicable treatment for my disease?
Your alteration in hormonal levels can be typical in TH1 disease.
Most supplements and many medications must be avoided on the MP.
Our clinical study is temporarily closed to enrollment. As vacancies occur, we will admit subjects based on an application. To obtain an application form, please send an email to marshallprotocol2@yahoo.com with 'request MP application' in the subject line.
Best, P.B.
____________________
Nothing contained in this site is or should be considered, or used as a substitute for, medical advice, diagnosis or treatment by your physician.
|
vip.5678
Member
| Joined: | Fri Sep 5th, 2008 |
| Location: | |
| Posts: | 12 |
| Status: |
Offline
|
|
Posted: Sat Sep 27th, 2008 08:57 |
|
Thanks a lot for interpretation.
This is a big problem with me. I am always on border line in most of the tests. I don't get diagnosis.
I had clearly instructed lab to handle the sample as per the instructions given on MP website. Sample was collected by a satellite lab and was sent to Quest, internationally.
I will try to ask Quest if they received sample in frozen condition or not.
I think instead of getting another tests , I will start on theraupetic probe to see if if I experience immunopathology.
I would like to ask some questions which is related indirectly to MP.
Damage to HPA (Hypothalamus-Pituitary-Adrenal) Axis, is a known cause of CFS ( Chronic Fatigue Syndrome). Chronic stress and sleep deprivation over a long period can result in disorders of HPA axis. (As is in my case, i suspect it)
MP, helps improve immune system by killing CWD bacteria. I believe there is a possibility that HPA axis can improve because of this.
I would like to know if any studies have been done on HPA axis and Marshall Protocol.
Is there any data collected to see if pituitary and hypothalamic hormone, like ACTH and CRH show improvement in people undergoing MP.
Also, Is there any thing else I need to know before I start on Phase I of MP (apart from reading instruction on MP website).
Thanks,
Joy.
|
P.Bear R.N.
Research Staff
|
Posted: Sun Sep 28th, 2008 03:44 |
|
I would read all of:
Essential Information About the MP (Required Reading)
Marshall Protocol FAQs (Required Reading)
In our understanding damage to HPA is caused by chronic infection in CFS and elevation in 1,25-D, and normal hormonal homeostasis returns as infection is eliminated.
best, P.B.
____________________
Nothing contained in this site is or should be considered, or used as a substitute for, medical advice, diagnosis or treatment by your physician.
|
Current time is 15:14 | |
|
|
|
|
