My primary diagnosis is CFS with seven-year-old history. Samples were drawn at Quest Diagnostic India head quarter on 9th September 25, 2008 and were frozen before transporting to main lab in US. I am a vegetarian and my 25D level is <4 ng/ml and 1,25D level is 38 pg/ml. I was avoiding sun for more than one month to get relieve from my symptoms but started sun exposure five to seven days prior to sample collection.
I am not taking any Vit D supplement, any immunosuppressant drug or any other supplement.
Please help me assess my Vit D level as results are not giving any clear picture
Thanks
Shkull
____________________ CFS(7yrs)/Mild Kidney Stenosis/All blood and
CTs normal/Vegetarian/Pre MP D-25 <4ngml D-1,25 38pgml as on 09 sep 08/no OTC/no Med/avoiding Sun/NOIRs-Finding Doc
Your 1,25-D is somewhat elevated at 38 pg/ml (the population average is 25-29 pg/ml). It is 0.95 sigma high and based on population studies, 82.90% of the population would be expected to have a lower number. If sample was permitted to thaw at any point in transit results would have been higher. Since in our experience those with CFS usually have a higher number this is a possibility?
Your 25-D of less than 4 ng/ml is low even for a vegetarian and is a strong indication of TH1 disease process. High levels of 1,25-D inhibit the conversion of vitamin D into 25-D resulting in a low level of 25-D. Because 25-D is immunosuppressive, you would still need to avoid ALL sources of Vitamin D to keep it lower than therapeutic level of 12ng/ml. Please see Foods To Avoid and The importance of avoiding vitamin D.
"The 25-D seems to be the most critical factor as to whether the immune system is able to start working. Any level of 25-D above about 20ng/ml is likely to be acting as an immunosuppressant, with an action very similar to that of corticosteroids." Dr. Trevor Marshall, Ph.D.
Our clinical study is temporarily closed to enrollment. As vacancies occur, we will admit subjects based on an application. To obtain an application form, please send an email to marshallprotocol2@yahoo.com with 'request MP application' in the subject line.
Best, P.B.
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