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wind flower
Member
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Posted: Sat Aug 16th, 2008 04:40 |
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Good evening, this is my first post on your site. recently diagnosed with rheumatoid arthritis.
had blood drawn 7/15/08 by Quest laboratory. Sample was frozen.
Had greatly reduced vitamin d food and sunlight since 6/1/08
currently taking minocyclene 50 mg. m-w-f since 4/25/08 for RA-tested ppositive (200 titer) for micoplasma pneumonia
magnolia bark for depression
ibuprofen as needed for pain
took prednisone approx. 8 years ago for ongoing sinus and chest infection, nothing taken since
fish oil, flax seed etc taken regularly until 7/08 then stopped all supplements
never taken benecar,ARB or ACE inhibitors
test results:
vitamin d, 25-oh , total 36; d3 36; d2,4
vitamin d, 1,25 65
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P.Bear R.N.
Research Staff
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Posted: Sat Aug 16th, 2008 05:44 |
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Sweetpea,
Your 1,25-D is elevated at 65pg/ml (the population average is 25-29 pg/ml). It is 3.79 sigma high and based on population studies, 100% of the population would be expected to have a lower number.
Your 1,25-D is above the maximum of 45pg/ml listed in the Merck Manual of Diagnosis and Therapy (15 Oct 2006 online). At levels above about 42 pg/ml, the 1,25-D (generated by the Th1 inflammation) begins to stimulate bone osteoclasts, causing bone to be resorbed (dissolved) back into the bloodstream. Not only does this lead to osteoporosis, but also to calcium being deposited into soft tissue of the body, including the lungs, breasts, and the kidneys (where it forms kidney stones). Please see Osteoporosis, osteopenia and Th1 illness.
Your level of elevation suggests inflammation in major organs such as heart, liver and lungs.
When should I be concerned about cardiac symptoms?
Your 25-D of 36ng/ml is high and reflects your reported vitamin D supplementation. Because 25-D is immunosuppressive, you need to avoid ALL sources of Vitamin D to get it down to a therapeutic level of 12ng/ml or less. Please see Foods To Avoid and The importance of avoiding vitamin D.
"The 25-D seems to be the most critical factor as to whether the immune system is able to start working. Any level of 25-D above about 20ng/ml is likely to be acting as an immunosuppressant, with an action very similar to that of corticosteroids." Dr. Trevor Marshall, Ph.D.
Your D-tests, diagnosis and symptoms indicate Th1 inflammation. Please see Symptoms of Hypervitaminosis-D and you may recognize a few more. You will not get well and your health will continue to deteriorate if you don't treat the underlying bacterial cause of Th1 inflammation with the MP. Please see Is the MP an applicable treatment for my disease?
Most supplements and many medications must be avoided on the MP. In my opinion magnolia bark is too big of an unknown, since a great many botanicals modulate immune function.
Our clinical study is temporarily closed to enrollment. As vacancies occur, we will admit subjects based on an application. To obtain an application forum, please send an email to marshallprotocol2@yahoo.com with 'request MP application' in the subject line.
best, P.B.
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Nothing contained in this site is or should be considered, or used as a substitute for, medical advice, diagnosis or treatment by your physician.
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wind flower
Member
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Posted: Sat Aug 16th, 2008 06:08 |
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| thank you very much for your timely reply! It was as I assumed after reading the results of others on this site with the same levels. I'm not really sure what to do at this point. I have filled in my application for the MP, am avoiding all vitamin d foods, avoiding sunlight except on my commute to work, taking the minocyclene. thank you for your opinion on the magnolia bark. i should probably stop taking that as well. was hoping it would help with the depression that has been so difficult. thank you again, martha
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P.Bear R.N.
Research Staff
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Posted: Sat Aug 16th, 2008 08:07 |
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Sweetpea, Depression is frequently a companion of TH1 inflammation and we take it quite seriously. If need be anti-depressants can be tried and would be a good idea when suicidal ideation comes into play. They may interfere with MP to some extent and are to be avoided for mild depression; but some may need them until the bacterial load is reduced. Some have found that just using Benicar and keeping their 1,25-D levels down can be very effective in helping mood.
best, P.B.
____________________
Nothing contained in this site is or should be considered, or used as a substitute for, medical advice, diagnosis or treatment by your physician.
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wind flower
Member
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Posted: Sat Aug 16th, 2008 16:54 |
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thankyou for your encouraging words. the depression is not severe, no suicidal thoughts at all, however it is very constant-a black cloud that never goes away anymore. I don't think I would try antidepressants again because of the very bad side affects I experienced years ago. Not interested in going that route.
THe use of the benecar was the most appealing form of treatment when i was researching this disease mainly due to its success in balancing hormones and help with mood. I am anxious to start. I am interesting in treating the whole mind & body, for me that is the only answer. The past few days I have experienced my worst herxing so far. that was what prompted my post-i'm glad i did. thank you.
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