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LB
Member
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Posted: Wed Aug 13th, 2008 02:08 |
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-The date the blood was drawn- 7/22/08
-Which lab did the tests? Quest
-Was the 1,25-D sample was frozen for shipment? Unknown, called Quest and they will not provide the patient with that information.
-How long have you been avoiding foods with vitamin D in them? Was not avoiding 100%.
-How long have you been avoiding sun/lights? Was not avoiding 100%.
-List all meds, supplements (both prescription and OTC) you have been taking and why.
Synthroid 75mg/day for Hashimoto's Thyroiditis.
Generic Prilosec 40mg/day-heartburn
Quit taking supplements for about 1 month,
Tylenol for headaches and BAD period cramps (1-4 per month).
-When and for how long have you taken prednisone or any other immunosuppressant in any form?
Prednisone-May 2006 thru Nov 2006
Symbicort inhaler for 1 month-June 2008
Nasonex-June 2008
Veramyst- July 2008 until August 12, 2008.
-When and for how long did you take Vitamin D supplements (including any vitamin-mineral supplements), omega-3 supplements and/or any kind of fish oil? Stopped taking ALL Vitamin D supplements & fish oil caps June 2008.
-Were you taking Benicar when the sample was drawn? No.
-Were you taking an ARB or or an ACE inhibitor when the sample was drawn? No.
- Please add the required signature line - sarcoidosis(lung)5-06/hashimoto thyroiditis 7-07/hair loss/no MP yet/no lite measurements yet/seeing MP MD next week.
When we analyze the results, we take all of the above into account.
Include the measurements for both tests, 1,25D & 25D, noting either ng/ml and pg/ml or the metric equivalent; nmol or pmol.* (ug/l = ng/ml)
82 pmol/L = 34.2 pg/ml
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pulm sarc 5-06/hashi thyroid 7-07/ 1,25=82pg/mL 7-08
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LB
Member
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Posted: Wed Aug 13th, 2008 02:20 |
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Oh yeah, I also have PVC's on occasion. DX'd June 2008
Echocardiogram shows heart looks/works normal.-July 2008
Night sweats since March 2008 around the time my hair started to fall out once again. My hair started to fall out Sept 2007 and started growing back Dec 2007 to only fall out once again end of March 2008.Last edited on Wed Aug 13th, 2008 03:04 by LB
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pulm sarc 5-06/hashi thyroid 7-07/ 1,25=82pg/mL 7-08
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P.Bear R.N.
Research Staff
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Posted: Wed Aug 13th, 2008 07:28 |
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LB,
Your 1,25-D is elevated at 34.2 pg/ml (the population average is 25-29 pg/ml). It is 0.55 sigma high and based on population studies, 70.65 % of the population would be expected to have a lower number.
You will need to have your 25-D measured as well. Because 25-D is immunosuppressive, you need to avoid ALL sources of Vitamin D to get it down to a therapeutic level of 12ng/ml or less. Please see Foods To Avoid and The importance of avoiding vitamin D.
Higher levels of 25-D can depress 1,25-D reading so your 1,25-D reading may have been even higher if you had been avoiding D3 and D2 longer.
"The 25-D seems to be the most critical factor as to whether the immune system is able to start working. Any level of 25-D above about 20ng/ml is likely to be acting as an immunosuppressant, with an action very similar to that of corticosteroids." Dr. Trevor Marshall, Ph.D.
Your D-tests, diagnosis and symptoms indicate Th1 inflammation. Please see Symptoms of Hypervitaminosis-D and you may recognize a few more. You will not get well and your health will continue to deteriorate if you don't treat the underlying bacterial cause of Th1 inflammation with the MP. Please see Is the MP an applicable treatment for my disease?
Most supplements and many medications must be avoided on the MP.
Our clinical study is temporarily closed to enrollment. As vacancies occur, we will admit subjects based on an application. To obtain an application forum, please send an email to marshallprotocol2@yahoo.com with 'request MP application' in the subject line.
best, P.B.
____________________
Nothing contained in this site is or should be considered, or used as a substitute for, medical advice, diagnosis or treatment by your physician.
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LB
Member
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Posted: Wed Aug 13th, 2008 14:55 |
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P. Bear,
Thank you so much for your quick work!  What a TRUE blessing it has been to find MP and helpful people. In the past several days, I have been making print outs and will be making a "MP Binder" with all the necessary information (hopefully  ) at my fingertips.
Goddness! These test have me all messed up!
I looked at the test again. It IS from Quest. The number says 82 (out of range). Then next to it it has reference range 15-60pg/mL. So I think the 82 is already converted to the pg/mL. I THINK I ended up posting the wrong number. Ugh! I feel SOOOO stupid!
So with this number (82), I think I will get the "cardiac" link, hu? I was hoping to avoid that.
Thank you again for all your help! And THANK YOU to Dr. Marshall, Liz Marshall. Meg, Barb and all the others that are here to HELP others. Last edited on Wed Aug 13th, 2008 15:07 by LB
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pulm sarc 5-06/hashi thyroid 7-07/ 1,25=82pg/mL 7-08
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P.Bear R.N.
Research Staff
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Posted: Wed Aug 13th, 2008 22:13 |
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LB,
Your "new" 1,25-D is terribly elevated at 82pg/ml (the population average is 25-29 pg/ml). It is 5.58 sigma high and based on population studies, 100% of the population would be expected to have a lower number.
Your 1,25-D is above the maximum of 45pg/ml listed in the Merck Manual of Diagnosis and Therapy (15 Oct 2006 online). At levels above about 42 pg/ml, the 1,25-D (generated by the Th1 inflammation) begins to stimulate bone osteoclasts, causing bone to be resorbed (dissolved) back into the bloodstream. Not only does this lead to osteoporosis, but also to calcium being deposited into soft tissue of the body, including the lungs, breasts, and the kidneys (where it forms kidney stones). Please see Osteoporosis, osteopenia and Th1 illness.
Your level of elevation suggests inflammation in major organs such as heart, liver and lungs.
When should I be concerned about cardiac symptoms?
You will still need to have your 25-D measured as well. Because 25-D is immunosuppressive, you need to avoid ALL sources of Vitamin D to get it down to a therapeutic level of 12ng/ml or less. Please see Foods To Avoid and The importance of avoiding vitamin D.
Higher levels of 25-D can depress 1,25-D reading so your 1,25-D reading may have been even higher if you had been avoiding D3 and D2 longer.
"The 25-D seems to be the most critical factor as to whether the immune system is able to start working. Any level of 25-D above about 20ng/ml is likely to be acting as an immunosuppressant, with an action very similar to that of corticosteroids." Dr. Trevor Marshall, Ph.D.
Your D-tests, diagnosis and symptoms very strongly indicate Th1 inflammation. Please see Symptoms of Hypervitaminosis-D and you may recognize a few more. You will not get well and your health will continue to deteriorate if you don't treat the underlying bacterial cause of Th1 inflammation with the MP. Please see Is the MP an applicable treatment for my disease?
best, P.B.
____________________
Nothing contained in this site is or should be considered, or used as a substitute for, medical advice, diagnosis or treatment by your physician.
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LB
Member
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Posted: Thu Sep 11th, 2008 22:17 |
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-The date the blood was drawn- 8/20/08
-Which lab did the tests? Quest
-Was the 1,25-D sample was frozen for shipment? Yes
-How long have you been avoiding foods with vitamin D in them? Was not avoiding 100%, but have for the most part.
-How long have you been avoiding sun/lights? Was not avoiding 100%, but have been using sunscreen when out.
-List all meds, supplements (both prescription and OTC) you have been taking and why.
Synthroid 75mg/day for Hashimoto's Thyroiditis.
Tylenol for headaches and BAD period cramps (1-4 per month).
-When and for how long have you taken prednisone or any other immunosuppressant in any form?
Prednisone-May 2006 thru Nov 2006
Symbicort inhaler for 1 month-June 2008
Nasonex-June 2008
Veramyst- July 2008 until August 12, 2008.
-When and for how long did you take Vitamin D supplements (including any vitamin-mineral supplements), omega-3 supplements and/or any kind of fish oil? Stopped taking ALL Vitamin D supplements & fish oil caps June 2008.
-Were you taking Benicar when the sample was drawn? No.
-Were you taking an ARB or or an ACE inhibitor when the sample was drawn? No.
- Please add the required signature line - sarcoidosis(lung)5-06/hashimoto thyroiditis 7-07/hair loss/no MP yet/no lite measurements yet/seeing MP MD, he will not give meds yet.
NEW TEST RESULTS...
VITAMIN D 1,25 HYDROXY 61 pg/mL
VITAMIN D 25,OH 15 ng/mL
____________________
pulm sarc 5-06/hashi thyroid 7-07/ 1,25=82pg/mL 7-08
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P.Bear R.N.
Research Staff
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Posted: Fri Sep 12th, 2008 20:31 |
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LB, Here is the analysis of new test results:
Your 1,25-D is very elevated at 61pg/ml (the population average is 25-29 pg/ml). It is 3.37 sigma high and based on population studies, 99.95% of the population would be expected to have a lower number.
Your 1,25-D is above the maximum of 45pg/ml listed in the Merck Manual of Diagnosis and Therapy (15 Oct 2006 online). At levels above about 42 pg/ml, the 1,25-D (generated by the Th1 inflammation) begins to stimulate bone osteoclasts, causing bone to be resorbed (dissolved) back into the bloodstream. Not only does this lead to osteoporosis, but also to calcium being deposited into soft tissue of the body, including the lungs, breasts, and the kidneys (where it forms kidney stones). Please see Osteoporosis, osteopenia and Th1 illness.
Your level of elevation suggests inflammation in major organs such as the heart, liver and lungs.
When should I be concerned about cardiac symptoms?
Your 25-D of 15ng/ml is lower than might be expected given your previous D supplementation, but high levels of 1,25-D will depress 25-D levels. Because 25-D is immunosuppressive, you still need to avoid ALL sources of Vitamin D to get it down and keep it down to a therapeutic level of 12ng/ml or less. Please see Foods To Avoid and The importance of avoiding vitamin D.
"The 25-D seems to be the most critical factor as to whether the immune system is able to start working. Any level of 25-D above about 20ng/ml is likely to be acting as an immunosuppressant, with an action very similar to that of corticosteroids." Dr. Trevor Marshall, Ph.D.
Your D-tests, diagnosis and symptoms indicate Th1 inflammation. Please see Symptoms of Hypervitaminosis-D and you may recognize a few more. You will not get well and your health will continue to deteriorate if you don't treat the underlying bacterial cause of Th1 inflammation with the MP. Please see Is the MP an applicable treatment for my disease?
Most supplements and many medications must be avoided on the MP.
Our clinical study is temporarily closed to enrollment. As vacancies occur, we will admit subjects based on an application. To obtain an application form, please send an email to marshallprotocol2@yahoo.com with 'request MP application' in the subject line.
Best, P.B.
____________________
Nothing contained in this site is or should be considered, or used as a substitute for, medical advice, diagnosis or treatment by your physician.
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