 |
| Author | Post |
|---|
mspatient
Member
| Joined: | Wed May 21st, 2008 |
| Location: | |
| Posts: | 15 |
| Status: |
Offline
|
|
Posted: Wed Aug 6th, 2008 23:00 |
|
Briefly list your diagnosis or symptoms. (around 2 lines at the most).
In March of 2006 diagnosed with MS. Had numbness and tingling on left side of body. Other symptom: vertigo, double vision, facial paralysis. In August 2007, was encouraged to be tested for Lyme (Igenex, western blot) – tested positive.
-The date the blood was drawn
6/1/08
-Which lab did the tests?
Quest Diagnostics
-Was the 1,25-D sample was frozen for shipment?
yes
-How long have you been avoiding foods with vitamin D in them?
Haven’t avoided them yet.
-How long have you been avoiding sun/lights?
Haven’t avoided sun/lights yet.
-List all meds, supplements (both prescription and OTC) you have been taking and why.
Beta Seron (MS), provigil (fatigue), at times this year (inconsistently): a multivitamin, fish oil supplement, vit B supplement. From October 2007 – January 2008 took antibiotics prescribed by LLMD, included Ceftin, Doxycycline, Zithromax.
-When and for how long have you taken prednisone or any other immunosuppressant in any form?
Beta Seron (March 2006 – April 2008)
Solumedrol (Feburary 2006 and April 2006) one week each time
-When and for how long did you take Vitamin D supplements (including any vitamin-mineral supplements), omega-3 supplements and/or any kind of fish oil?
Off and on since October 2007. Haven’t taken any in about 3 or 4 months
-Were you taking Benicar when the sample was drawn?
No
-Were you taking an ARB or or an ACE inhibitor[size=]when the sample was drawn?
No
Include the measurements for both tests, 1,25D & 25D, noting either ng/ml and pg/ml or the metric equivalent; nmol or pmol.* (ug/l = ng/ml)
I was only told that my D25 was 28 and my D1,25 was 72
____________________
diagnosed with MS and Lyme, starting the MP September 8, 2008, D1,25: 72, D25: 28, beta seron, provigil
|
P.Bear R.N.
Research Staff
|
Posted: Thu Aug 7th, 2008 01:21 |
|
MSpatient,
I am assuming you are in USA since you used Quest for D panel and will use U.S. measuring standards. By the way you are entitled by law to have copies of your lab reports if requested and sign a release.
Your 1,25-D is very elevated at 72pg/ml (the population average is 25-29 pg/ml). It is 4.53 sigma high and based on population studies, 100% of the population would be expected to have a lower number.
Your 1,25-D is above the maximum of 45pg/ml listed in the Merck Manual of Diagnosis and Therapy (15 Oct 2006 online). At levels above about 42 pg/ml, the 1,25-D (generated by the Th1 inflammation) begins to stimulate bone osteoclasts, causing bone to be resorbed (dissolved) back into the bloodstream. Not only does this lead to osteoporosis, but also to calcium being deposited into soft tissue of the body, including the lungs, breasts, and the kidneys (where it forms kidney stones). Please see Osteoporosis, osteopenia and Th1 illness.
Your level of elevation suggests inflammation in major organs such as heart, liver and lungs.
When should I be concerned about cardiac symptoms?
Your 25-D of 28ng/ml is high enough to mute innate immune response. Because 25-D is immunosuppressive, you need to avoid ALL sources of Vitamin D to get it down to a therapeutic level of 12ng/ml or less. Please see Foods To Avoid and The importance of avoiding vitamin D.
"The 25-D seems to be the most critical factor as to whether the immune system is able to start working. Any level of 25-D above about 20ng/ml is likely to be acting as an immunosuppressant, with an action very similar to that of corticosteroids." Dr. Trevor Marshall, Ph.D.
Your D-tests, diagnosis and symptoms indicate Th1 inflammation. Please see Symptoms of Hypervitaminosis-D and you may recognize a few more. You will not get well and your health will continue to deteriorate if you don't treat the underlying bacterial cause of Th1 inflammation with the MP. Please see Is the MP an applicable treatment for my disease?
Most supplements and many medications must be avoided on the MP. We encourage you to stop fish oil, multivitamin, and provigil that can only have short term benefits and cause long term problems.
Our clinical study is temporarily closed to enrollment. As vacancies occur, we will admit subjects based on an application. To obtain an application forum, please send an email to marshallprotocol2@yahoo.com with 'request MP application' in the subject line.
best, P.B.
____________________
Nothing contained in this site is or should be considered, or used as a substitute for, medical advice, diagnosis or treatment by your physician.
|
mspatient
Member
| Joined: | Wed May 21st, 2008 |
| Location: | |
| Posts: | 15 |
| Status: |
Offline
|
|
Posted: Thu Aug 7th, 2008 04:22 |
|
| With that level of inflamation in those major organs, along with the MS diagnosis, do you think I will be able to handle the IP from the MP? My wife is nervous that the treatment might cause more damage than my body can handle.
____________________
diagnosed with MS and Lyme, starting the MP September 8, 2008, D1,25: 72, D25: 28, beta seron, provigil
|
P.Bear R.N.
Research Staff
|
Posted: Thu Aug 7th, 2008 05:54 |
|
If treatment is slow with controlled immunopathology most people would be able to tolerate MP without any organ damage. I myself had vertigo, double vision and facial paralysis with numbing hands and feet and was able to do well even though the first year was very hard. The MP is not for the weak at heart as it can make you feel bad as you kill the bugs. Some will find it too hard, but the alternative of palliative treatment only means just a slow decline I am afraid in the vast majority. A support system is important for anyone who is so seriously ill. This is a hard choice; but at least we now have a choice.
P.B.
____________________
Nothing contained in this site is or should be considered, or used as a substitute for, medical advice, diagnosis or treatment by your physician.
|
Current time is 23:19 | |
|
|
|
|
