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baypilot
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Joined: Thu Oct 9th, 2008
Location: Turkey
Posts: 17
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 Posted: Tue Oct 14th, 2008 09:28

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why some patients who use steroid and remission than no relapse?

thank u



____________________
-Sarcoidosis/lymph nodes mediastine/shortness of breath stageI(DEC06)
-Initial 1,25D50 25D23(nov08)
-no star phase one
-Latest 125d50 25D23(nov08)
-no Medications in use
-NoIRs covered up Low lux home exp work
Julia
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Location: Belfast, United Kingdom
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 Posted: Tue Oct 14th, 2008 17:08

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Hi Baypilot,

Steroids suppress the immune system, reducing inflammation so that you feel better for a while, but the bacteria causing your disease are not being killed.  This 'remission' is just a brief period of feeling better, but when you stop taking the steroids you have a relapse.  I haven't heard of anyone not relapsing eventually, have you?

"What is the Marshall Protocol?"

Simple Explanations

Success Stories

Bacteriality - a readable blog-style website by one of our members, with science-made-easy articles, an introductory 90-minute video, and interviews with recovering patients - an excellent introduction to the MP.

Please ask any further questions here at your own personal thread :)

Julia 



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Always consult a physician
Essential Info; FAQ; Julia's story
baypilot
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 Posted: Tue Oct 14th, 2008 20:35

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does  Dr marshall wants payment for other phases ?

thank u

Last edited on Tue Oct 14th, 2008 21:25 by baypilot



____________________
-Sarcoidosis/lymph nodes mediastine/shortness of breath stageI(DEC06)
-Initial 1,25D50 25D23(nov08)
-no star phase one
-Latest 125d50 25D23(nov08)
-no Medications in use
-NoIRs covered up Low lux home exp work
Julia
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Joined: Wed Oct 17th, 2007
Location: Belfast, United Kingdom
Posts: 1338
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 Posted: Wed Oct 15th, 2008 00:36

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No, there is no charge for the MP.  Phases 2 and 3 are not available to the public for safety reasons.  But your prescribing doctor can join the private health professionals' forum where there is access to the whole protocol from the start, as well as support and advice from our medical team.



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Always consult a physician
Essential Info; FAQ; Julia's story
baypilot
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 Posted: Sat Oct 18th, 2008 12:35

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hi Julia
what about the sarcoidossis vaccine? .Is there any vaccinal study?

thank u



____________________
-Sarcoidosis/lymph nodes mediastine/shortness of breath stageI(DEC06)
-Initial 1,25D50 25D23(nov08)
-no star phase one
-Latest 125d50 25D23(nov08)
-no Medications in use
-NoIRs covered up Low lux home exp work
Julia
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Joined: Wed Oct 17th, 2007
Location: Belfast, United Kingdom
Posts: 1338
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 Posted: Sat Oct 18th, 2008 12:46

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I've heard that a vaccine for sarcoidosis in horses has recently been developed, with limited success, but I haven't heard of one for humans.  The disease is caused by bacteria, and can be treated very successfully with the MP.



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Always consult a physician
Essential Info; FAQ; Julia's story
baypilot
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Location: Turkey
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 Posted: Sat Oct 18th, 2008 14:39

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 Does hawthorn effect angiotensin II receptor like olmesartan? ıs there any study about it? or ıs there any naturel food affect angiotensin II receptor like olmesartan?

thank u

Last edited on Sat Oct 18th, 2008 14:41 by baypilot



____________________
-Sarcoidosis/lymph nodes mediastine/shortness of breath stageI(DEC06)
-Initial 1,25D50 25D23(nov08)
-no star phase one
-Latest 125d50 25D23(nov08)
-no Medications in use
-NoIRs covered up Low lux home exp work
Julia
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Joined: Wed Oct 17th, 2007
Location: Belfast, United Kingdom
Posts: 1338
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 Posted: Sat Oct 18th, 2008 18:14

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Hawthorn is thought to act like an ACE inhibitor, but olmesartan is an Angiotensin Receptor Blocker.  See Benicar Applications Beyond Hypertension, especially the section ARBs vs ACE Inhibitors.

If there was a natural food that acted the same as olmesartan our members wouldn't be struggling to get doctors to prescribe Benicar :(



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Always consult a physician
Essential Info; FAQ; Julia's story
baypilot
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 Posted: Fri Oct 24th, 2008 11:05

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my doctor said that why olmesartan.why we dont use other  Anjiyotensin II antagonist? Is there any  Anjiyotensin II antagonist? does he right?  thank u



____________________
-Sarcoidosis/lymph nodes mediastine/shortness of breath stageI(DEC06)
-Initial 1,25D50 25D23(nov08)
-no star phase one
-Latest 125d50 25D23(nov08)
-no Medications in use
-NoIRs covered up Low lux home exp work
Julia
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Joined: Wed Oct 17th, 2007
Location: Belfast, United Kingdom
Posts: 1338
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 Posted: Fri Oct 24th, 2008 13:29

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See How does Benicar work?  Dr Marshall has studied the Angiotensin Receptor Blockers (ARBs) in detail, and Olmesartan is the only one that acts on the Vitamin D Receptor (VDR) in just the way necessary to restore the function of the infected immune system.
The VDR Nuclear Receptor is key to the operation of the innate immune system, that part of the immune system which will attack intraphagocytic organisms. The VDR controls key elements of the body's innate immune response. The ARB Benicar dose-proportionally inhibits the runaway VDR in order to allow the innate immune system to operate again (the pathogens get it into an inoperable state by generating too much 1,25-D and possibly by generating cofactor-toxins as well).

Some other drugs, especially the azoles, also affect the operation of the D-metabolites, and/or the VDR. But they do it in a manner which is not dose-controllable, as Benicar does. Additionally, Benicar affects a number of other key receptors as well, and just happens to have a near-perfect mix of actions, from the point of view of making innate immunity function again, even in the continued presence of the pathogens.

[from The Need for a Benicar Blockade in the article Cell Wall Deficient Bacteria and the MP]

Perhaps your doctor would like to join the private Forum for Health Professionals, where he can ask questions and find out more about the MP, and also access the whole MP from the start.



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Always consult a physician
Essential Info; FAQ; Julia's story
baypilot
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 Posted: Fri Oct 24th, 2008 13:53

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I COULDNT PERSUADE DOCTORS, THEY ARE DOUPTFUL ABOUT MP AND THEY DONT İNTERES İN MP .I DONT KNOW HOW CAN I PERSUADE THEM ? olsa I need a doctor for guindace



____________________
-Sarcoidosis/lymph nodes mediastine/shortness of breath stageI(DEC06)
-Initial 1,25D50 25D23(nov08)
-no star phase one
-Latest 125d50 25D23(nov08)
-no Medications in use
-NoIRs covered up Low lux home exp work
Julia
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Joined: Wed Oct 17th, 2007
Location: Belfast, United Kingdom
Posts: 1338
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 Posted: Fri Oct 24th, 2008 14:06

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I'm sorry to hear that.  Sadly it's a common complaint :(  See Suggestions To Get Your Doctor On Board With the MP.  If you can just find a doctor to prescribe the MP medications, you can find all the information you need on our main site in the following links:

Phase1 guidelines - print one out for you and one for your doctor, and refer to it often.

FAQs Easy Finder & the ABC of MP - use with the search facilities to find information.  How to do a site search

Essential Information About the MP - take this a little at a time!

Then when you start the MP, you can post in our forum Non-medical support for those on MP, where you can get support from more experienced members, and links to any information you need.



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Always consult a physician
Essential Info; FAQ; Julia's story
baypilot
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 Posted: Sat Oct 25th, 2008 22:20

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If I can take medications without doctor can I take Phase2 and Phase3 guidelines

I mean cant I be member marshall forum without doctor? little bit confused



____________________
-Sarcoidosis/lymph nodes mediastine/shortness of breath stageI(DEC06)
-Initial 1,25D50 25D23(nov08)
-no star phase one
-Latest 125d50 25D23(nov08)
-no Medications in use
-NoIRs covered up Low lux home exp work
Julia
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Joined: Wed Oct 17th, 2007
Location: Belfast, United Kingdom
Posts: 1338
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 Posted: Sat Oct 25th, 2008 23:38

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Baypilot, you can't do the Marshall Protocol without a doctor to prescribe the medications and monitor you, it would not be safe.  We are not doctors, so we can only share our experience as long-term members, or guide you to the information you need in the vast MP 'library' on the main site.  For medical advice you must consult your doctor.

All doctors are welcome to join the private Professionals' Forum, where all the help and support they need is available, as well as access to the whole protocol from the start.  Phases 2 & 3 of the MP are not available in the public part of the site, so you must ask your doctor to print you out a copy of the Phase 2/3 guidelines when the time comes. 

While there is no medical support available here, you're welcome to ask non-medical questions that can be answered by more experienced members.   



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Always consult a physician
Essential Info; FAQ; Julia's story
baypilot
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 Posted: Sun Nov 2nd, 2008 18:33

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in Phase one we use only  minocyline.but L-form bacteries have  antibiotic resistant.how is kill mino them ? thank u



____________________
-Sarcoidosis/lymph nodes mediastine/shortness of breath stageI(DEC06)
-Initial 1,25D50 25D23(nov08)
-no star phase one
-Latest 125d50 25D23(nov08)
-no Medications in use
-NoIRs covered up Low lux home exp work
JoshR
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 Posted: Mon Nov 3rd, 2008 01:21

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There are many different species of bacteria involved, and not all of them are resistant to minocycline. But the fact that some of them are resistant is why it is so important to use the phase 2 and 3 antibiotic combinations.



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5/6 CFS criteria, 125D36 Ph1Jul08 Ph2Sep08 25D8(Sep08) NoIRs covered up (except hands) low lux home minimal light exp r/t work
Knochen
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 Posted: Mon Nov 3rd, 2008 01:45

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This link may help answer your questions
Won't the bacteria become immune/resistant to the antibiotics if I take them a long time?



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I can help you understand the recovery process, but only your physician is licensed to give you medical care.
baypilot
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 Posted: Thu Nov 6th, 2008 16:43

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'"A sarcoid patient's body is lacking some genes that limit the maximum concentration of 1,25-D." is it true?
thank u



____________________
-Sarcoidosis/lymph nodes mediastine/shortness of breath stageI(DEC06)
-Initial 1,25D50 25D23(nov08)
-no star phase one
-Latest 125d50 25D23(nov08)
-no Medications in use
-NoIRs covered up Low lux home exp work
edj2001
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Joined: Mon Oct 29th, 2007
Location: Allen, Texas USA
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 Posted: Fri Nov 7th, 2008 06:23

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Hello Baypilot

I just posted the message below to Lugubrious's question about the MP science.  It may help you to read the links referenced.  While you are at Amy's Bacteriality site spent some time there as there are many articles that will help you to better understand the MP science. 

Lug's link:    http://curemyth1.org/forum2/533.html

Gene


"Hello Lug,

Here are a couple of reference links with more detail about VDR homeostasis that can be found at Amy’s web site and Dr. Marshall’s BioEssay paper.  You may want to read these again.

Remember, the VDR is unable to regulate 1,25-D when intracellular bacterial infection and/or biofilms produce a protein (such as capnine) that acts as an antagonist to the VDR ligand.  This prevents VDR homeostasis and results in high levels of 1,25-D that then interfere with other receptors. Benicar acts as an agonist to the VDR and in high enough concentration can displace the bacterial protein antagonists allowing the VDR to function again.  Keeping 125-D low by avoiding sun helps this process.  

Gene

http://bacteriality.com/about-the-mp/

"...Furthermore, in healthy individuals, the VDR transcribes an enzyme called CYP24. CYP24 breaks down excess 1,25-D, ensuring that the level of 1,25-D in the body stays in the normal range. But in chronically ill individuals, the VDR (which is blocked by bacterial substances) can no longer transcribe CYP24. The level of 1,25-D in the body becomes significantly elevated since there is no CYP24 to keep it in check.

Another enzyme called CYP27B1 normally regulates the amount of 25-D converted into 1,25-D. When more CYP27B1 is produced, conversion occurs at a greater rate. The cytokines released by the immune system in response to the Th1 pathogens activate a protein called Protein Kinase A (PKA). PKA in turn activates CYP27B1, causing more 25-D to be converted to 1,25-D.

These processes cause 1,25-D to rise to an unnaturally high level. Unfortunately, when 1,25-D reaches a certain threshold, it binds not just the VDR, but many of the body’s other nuclear receptors, displacing the metabolites that are meant to be in the receptors under normal conditions.

The nuclear receptors affected by 1,25-D are receptors that regulate the body’s hormones - the glucocorticoid receptor, and the alpha and beta thyroid receptors, the adrenal receptors, and the progesterone receptors, among others..."

And Dr Marshall’s paper:
 http://trevormarshall.com/BioEssays-Feb08-Marshall-Preprint.pdf

“…For half a century, medical science has been noting the association between Vitamin D serum levels and disease. What developed has been a concept of ‘Vitamin D Deficiency’ based solely on the assumption that ‘low’ Vitamin D serum levels somehow cause disease processes. But this ignores the alternate hypothesis -- that the disease processes themselves regulate the Vitamin D metabolism -- that the observed ‘low’ values of Vitamin D in disease are a result of the disease process, and not the cause…”



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Sarcoidosis 1998| MP Dec 05| Gene's Story| About MP| ABC of MP| Perspectives|
baypilot
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 Posted: Sun Nov 9th, 2008 20:27

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can ı use Zinc Oxide cream instead of Zinc Oxide sunscreen?

thank u.



____________________
-Sarcoidosis/lymph nodes mediastine/shortness of breath stageI(DEC06)
-Initial 1,25D50 25D23(nov08)
-no star phase one
-Latest 125d50 25D23(nov08)
-no Medications in use
-NoIRs covered up Low lux home exp work

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