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amigo
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Posted: Fri Oct 19th, 2007 22:01 |
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Any reason to believe that B12 deficiency is a result of Th1 inflammation (as a result of CWD bacteria and dysregulation of the D-metabolites)?
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Julia
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Posted: Fri Oct 19th, 2007 23:43 |
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Hi Amigo,
Welcome to this site. I don't think your question has a definite answer as yet, but you might be interested in this link: Vitamin B12 (Cobalamine).
Julia 
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amigo
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Posted: Sat Oct 20th, 2007 00:59 |
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study mentioning B12 deficiency, low 25D and high 1,25D levels...
http://tinyurl.com/22efhv
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Julia
Advocate (on leave)
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Posted: Sat Oct 20th, 2007 08:51 |
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Maybe the rats that had their stomachs removed suffered from post-operative Th1! It seems a drastic way to artificially induce B12 deficiency... I would have doubts about studying acutely disabled and traumatised rats and saying it had any relevance to slow-onset pernicious anaemia in whole humans, but then I'm not a scientist.
Are you asking because you're suffering from pernicious anaemia and wondering if the MP would help?
Julia
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amigo
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Posted: Sat Oct 20th, 2007 12:05 |
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I know someone who had B12 injections for deficiency and had complete symptom relief of fatigue, brain fog, difficulty sequencing tasks, inability to drive, memory problems, neck and back pain, headaches, word searching difficulties and vertigo requiring a cane.
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Julia
Advocate (on leave)
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Posted: Sat Oct 20th, 2007 12:32 |
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According to Wikipedia, the B12 deficiency in pernicious anaemia is most commonly caused by 'autoimmune gastritis', in which the intrinsic factor in the stomach (which should bind with the vitamin B12 in the diet) is destroyed.
Anaemia would cause your friend's symptoms. Taking B12 by injection would bypass the inflamed stomach lining, so it would make sense that the symptoms would be relieved.
But as for what caused the stomach inflammation in the first place, well, it does sound very like the other so-called autoimmune diseases that we now know are caused by Cell Wall Deficient bacteria. Maybe it would respond to the MP, but I don't know whether the stomach lining would recover to the point of no longer needing B12 injections.
Julia
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Dr Trevor Marshall
Research Team
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Posted: Sat Oct 20th, 2007 15:57 |
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Hey, let's not forget that Wikipedia is edited (mostly) by computer-tech geeks sitting at their keyboards, scanning PubMed for inspiration. It is not a reliable source, but by its nature is a "parrot" regurgitating what has been said before.
When dealing with the idiopathic diseases it is of little help to read what has been said before, because the people saying that were not able to reach a conclusion, and a solution. That is why the diseases are still idiopathic.
There is a big problem with the assumption that "Food makes the man." It doesn't. In fact, when the body starts down-regulating hormones and metabolites the body is usually doing that for a reason. The whole concept of "replacement" or "supplementation" is fraught with non-sequiturs and risks.
The classic case is, of course, Vitamin D. When the body down-regulates 25-D it does so because it already has too much of the metabolite. Giving the body even more is entirely the incorrect approach.
I do not know enough about Vitamin B12 to determine that it is not similar. You should not assume that just because your body is "low" in something that you should be adding a supplement. In the presence of a controlled metabolite, 'Deficiency' can be a non-sequitur. You have to know more about the underlying metabolite, and I haven't seen anything definitive about what B12 supplementation achieves at the molecular level to be at all confident of its asserted actions.
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P.Bear R.N.
Research Staff
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Posted: Mon Oct 22nd, 2007 09:01 |
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Amigo, There are several causes of low serum cobalamin levels. In gastrectomy the intrinsic factor is bypassed and replacement is required or pernicious anemia ensues. It is possible that CWD forms in the stomach tissue could be having an effect in some. Pernicious anemia as you may know will eventually kill you if untreated. Since B-12 is a true vitamin with known neurologic and hematologic effects in its absence it would make sense that a few people could have resolution of symptoms if they receive replacement of a real and profound physiologic deficiency. These clinical cases have been documented; with hematology studies returning to normal; peripheral neuropathies improving, mental status returning.
I tried replacement with methycobalamin (sublingual) and got my levels to move from rather low normal to very high normal pre-MP with no resolution in symptoms that were somewhat similar to the person you report on. I did not achieve symptom improvement and resolutions until undergoing MP treatment course. I would only recommend replacement if one has a documented deficiency and if ordered by a physician, or if one is a true vegan.
Hydroxycobalamin is used in ERs on occasion to help with stabilization of patients with certain chemical/ gas exposures like carbon monoxide and cyanide poisoning. In these acute cases it can be life saving, and it is given urgently.
best, P.B.
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amigo
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Posted: Sat Sep 6th, 2008 00:26 |
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Is there any reason to believe that the MP may help resolve impacted wisdom teeth in a teen such that it is better not having them extracted?
I didn't see anything related to this under the Dental Problems thread on the marshallprotocol.com site
thank you
Last edited on Sat Sep 6th, 2008 00:26 by amigo
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Julia
Advocate (on leave)
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Posted: Sat Sep 6th, 2008 21:50 |
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Amigo,
Welcome back!
See Is the MP an Applicable Treatment for my Disease?
Dental problems (I know you said you'd read this, but I'll give the link for anyone else who might be reading)
I can't find any references to impacted wisdom teeth in members' posts. We advise those who want to do the MP to avoid all surgery if at all possible, as Th1 patients don't heal well, and you never know what effect the MP is going to have on your symptoms anyway.
Julia 
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