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Cynthia Schnitz
Member
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Posted: Fri Aug 22nd, 2008 19:35 |
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In this document, the number for 1,25D that is supposed to represent dominant TH1 disease is given as >12 pg/ml. This seems much too low and perhaps some one put in the 25D number. It is in the yellow blocked section at the bottom, left, 2nd square down.
http://www.carouselcharts.com/MP_P1_QuickReference.pdf
Some where I came across the statement that 19-35 pg/ml of 1,25D is in the bone building/preserving range. Please pass this on to the responsible party, as I hope to have this corrected before I laminate it for my doctor. Cynthia
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Phase I 10-27-08, Calcium anomaly causes sensation of electricity thru chest, Spondylitis, TypeII diabetes(unconfirmed), returning sense of smell, sitting produces chilled state, finger ulcers
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Julia
Advocate (on leave)
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Posted: Fri Aug 22nd, 2008 20:43 |
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| Cynthia, I've asked someone knowledgeable to look into this.
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JoshR
Advocate
| Joined: | Mon Aug 18th, 2008 |
| Location: | Sydney, Australia |
| Posts: | 102 |
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Offline
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Posted: Sat Aug 23rd, 2008 12:53 |
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| The document also refers to 25D as "inert", which AIUI is incorrect.
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5/6 CFS criteria, 125D36 Ph1Jul08 Ph2Sep08 25D8(Sep08) NoIRs covered up (except hands) low lux home minimal light exp r/t work
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Julia
Advocate (on leave)
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Posted: Sat Aug 23rd, 2008 13:16 |
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Josh,
'Inert' is correct. 25-D is the biologically inert precursor to 1,25-D, the active hormone. See (for example) this summary by S W Stanbury, Royal Infirmary, Manchester, UK.
Vitamin D Tutorial
Julia 
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JoshR
Advocate
| Joined: | Mon Aug 18th, 2008 |
| Location: | Sydney, Australia |
| Posts: | 102 |
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Offline
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Posted: Sat Aug 23rd, 2008 17:52 |
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| Hmm, OK, I guess the word is being used in a different sense than I remember from my chemistry classes. It just seems odd to call 25-D inert when it does have a biological effect by displacing 1,25-D from the VDR. Last edited on Sat Aug 23rd, 2008 17:58 by JoshR
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5/6 CFS criteria, 125D36 Ph1Jul08 Ph2Sep08 25D8(Sep08) NoIRs covered up (except hands) low lux home minimal light exp r/t work
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Julia
Advocate (on leave)
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Posted: Tue Aug 26th, 2008 00:11 |
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Cynthia,
The chart you're referring to is a brief physician's summary. To understand the phrase you quote, you need to read it in context in the FAQ How often should I test D levels?, where Dr M is pointing out the difference between Th1 and Th2 dominance.
In part, it says, Folks with Th1 inflammatory symptoms who test low for 1,25-D do not have a Th2 immune system response. A level above 12pg/ml represents a dominant Th1 inflammatory response and disproves a dominant Th2 response. The population average is 25-29 pg/ml. It is above-average 1,25-D levels (hypervitaminosis-D) that cause many troublesome symptoms.
The quick-reference charts are designed for busy doctors, who already have the background medical knowledge.
Julia 
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